MY OLDER BIOLOGICAL BROTHER Dr. MICHAEL KIM McMILLAN OF THE UNIVERSITY OF SOUTHERN CALIFORNIA KECK MEDICAL SCHOOL STAFF ON JUNE 26, 2008, SENDS APPARENT ENDORSEMENT OF THE DIETARY SUPPLEMENT 'DHEA' IN A REPLY LETTER TO ME

 

----- Forwarded Message -----

From: Michael McMillan <mcmillan.mk@gmail.com>

To: "mcmillanj@att.net" <mcmillanj@att.net>

Sent: Thursday, June 26, 2008 at 10:18:14 AM MDT

Subject: Re: reply to Michael McMillan

DHEA is sold as a supplement; DHEAS is the form of the supplement that the body stores; COSTCO sells DHEA.

 

Mike

On Wed, Jun 25, 2008 at 8:50 PM, John McMillan <mcmillanj@att.net> wrote:

Dear Michael,

Thank you for that interesting item (below), and congratulations again on your new career as a chemist based at The University of Southern California Medical School in the Los Angeles area.

Do you know how to increase the DHEAS level in one's bloodstream?

Sincerely and Best Wishes,

your biological younger brother, John Kevin McMillan.

Phone: (512) 342-2295.

 

cc: Cousin Jim Dane, in the hope that this information might also be helpful to the many friendly gentlemen in the Dane and Gardner clans in Iowa.

 

John Kevin McMillan

----- Original Message ----
From: Michael McMillan <mcmillan.mk@gmail.com>
To: John McMillan <mcmillanj@att.net>
Sent: Tuesday, June 24, 2008 11:39:29 AM
Subject: DHEA

Long-term study links DHEAS to longevity in men

Reuters Health

Monday, June 23, 2008

NEW YORK (Reuters Health) - The amount of DHEAS that a man has in his blood is a "strong predictor" how long he will live, a new report from a 27-year study conducted in Japan suggests.

The adrenal glands secrete DHEAS, or dehydroepiandrosterone sulfate, a "pre-hormone," which the body converts into androgens and estrogens, Dr. Mika Enomoto and colleagues from Kurume University School of Medicine and colleagues explain. Levels of DHEAS peak during a person's 20s and 30s and then sharply decline.

Animal research has found the hormone has a number of anti-aging effects, they add, and some studies in humans have linked DHEAS levels to longevity, while others have not.

To better understand the relationship between DHEAS levels in humans and life span, the researchers measured DHEAS levels in 940 men and women who ranged in age from 21 to 88 in 1978, and followed them until 2005.

Men had higher levels of DHEAS at the study's outset, and both sexes showed a decline in levels of the hormone over time. In women, there was no relationship between their levels of DHEAS and how long they lived.

But for men, low levels of DHEAS, older age, higher blood pressure and higher blood sugar levels after fasting showed a significant association with shorter lifespan.

Among these variables, the researchers found that high levels of DHEAS were the most strongly linked to a longer life. The relationship between DHEAS and longevity remained even after the researchers adjusted for glucose levels, age and blood pressure.

But before the 15-year follow-up point, there was no difference in longevity among men based on DHEAS levels, the researchers note, which may help explain why some past research found no relationship between the hormone and longevity.

Limitations of the study include the fact that information on cause of death wasn't available for every participant, so it wasn't possible to determine if low DHEAS levels correlated with death from heart disease or other causes, the researchers say.

Nevertheless, they conclude the "these data suggest that serum level of DHEAS is a strong predictor of 27-year longevity in men."

SOURCE: Journal of the American Geriatrics Society, June 2008.